Areas of Expertise

• The role of glycolipid transfer proteins in cells
• Glycosphingolipid biosynthesis
• Intracellular glycosphingolipid transport events

Research Projects

• Glycolipid transfer protein, GLTP interaction with VAP-proteins in the ER exit sites
• The role of GLTP in demyelination
• Intracellular localization of GLTP
• Inhibitors for glycolipid binding proteins

Special Methodologies & Techniques

• Lipid biochemistry
• Quantitative and qualitative glycosphingo- and phospholipid analysis by high-performance TLC
• Cell and molecular biology
• Fluorescence spectroscopy, steady-state and lifetime
• Radioisotope labeling and lipid metabolism techniques

Major Funding & International Networks

• Medicinska understödsföreningen Liv och hälsa
• Borgs stiftelse
• COST action SPHINX member

Selected Publications

• Glycolipid transfer protein knockout disrupts vesicle trafficking to the plasma membrane. Journal of Biological Chemistry. 2023. DOI: 10.1016/j.jbc.2023.104607
• Who moves the sphinx? An overview of intracellular sphingolipid transport. BBA Molecular and Cell Biology of Lipids. 2021. DOI: 10.1016/j.bbalip.2021.159021
• Glucosylceramide acyl chain length is sensed by the glycolipid transfer protein. PLoS ONE. 2018. DOI: 10.1371/journal.pone.0209230
• Alternation in the Glycolipid Transfer Protein Expression Causes Changes in the Cellular Lipidome. PLoS ONE. 2014. DOI: 10.1371/journal.pone.0097263
• Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi. Nature. 2013. DOI: 10.1038/nature12423

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